Museo dell'Opera del Duomo is housed in a 13th century building in Piazza dei Miracoli, just a few metres from the Leaning Tower. The museum first opened in 1986 and was conceived as a location to contain the artefacts that had been removed from the Duomo and the Baptistry, while ensuring their protection and greater public use and accessibility.

The dilemma arose, in the wake of the July 1944 Camposanto monumentale roof fire, of how to best conserve the frescoes of the Camposanto and the relative sinopie (preliminary drawings), which had been revealed in 1974 with the first "tearing" of the overlying paintings.

Located in the medieval monastery of the same name near the river Arno, the National Museum of San Matteo boasts a rich series of works by leading Pisan and Tuscan masters of the 12^th-17^th centuries and a flourishing collection of archaeological and ceramic artifacts. The quantity and value of the exhibits make the San Matteo one of the most important European museums in the field of medieval art.

12^th- and 13^th-century painting is represented by the Croci dipinte (painted crosses), all derived from Pisa’s oldest churches, with works by Berlinghiero Berlinghieri, Giunta Pisano and the Master of San Martino.

The National Museum of the Palazzo Reale is housed in the 16th-century palazzo of the same name, designed by Buontalenti and for centuries home to the reigning families of the Medici, Lorena and Savoia. The palace was renovated in 2001, when spaces and connections with the adjoining buildings were restored.

The University of Pisa Museum of Natural History and Territory was founded in the early 1980s when the various universities merged their collections, transferring them to the Certosa di Calci.

Thanks to the importance and wealth of the collections, which bear witness to the four centuries of Pisan university research, this site has earned the reputation as one of the world's leading scientific museums. The earliest collections date back to the late 1500s.

The Art Gallery (Pinacoteca) and the Volterra Civic Museum are located in the Palazzo Minucci-Solaini. The Gallery features a remarkable group of paintings by Florentine, Sienese and Volterran artists.

The valuable wooden panels from the Florentine and Sienese schools, with polyptychs by Taddeo di Bartolo (Madonna enthroned with Child and Saints, signed and dated 1411) and Cenni di Francesco are exhibited alongside panels by Luca Signorelli (Annunciation) and Ghirlandaio (Christ in glory between saints and the client, abbot Giusto Bonvicini).

The Volterra Etruscan Museum was founded in the second half of the 1700s with the impressive collection of Mario Guarnacci. Over time the museum has grown thanks to fresh findings and acquisitions.
The museum contains artefacts from the protohistoric and Villanovan periods and a great number of findings from the time when Etruscan Volterra came into being, from the 4th to the 1st century B.C. There are also a number of 4th and 1st century B.C. Hellenistic materials on display.

The Diocesan Museum of Religious Art in Volterra contains collections of works originating from the Duomo (Cathedral) and the churches of the diocese: paintings, sculptures, goldsmith art, furnishings, manuscripts, religious hangings and the only surviving marble of the 14th century monuments of the Cathedral with works by Tino di Camaino, Angolo di Venura and Agostino di Giovanni.

The Piaggio Museum was founded in 2000 with the aim of preserving the historical memory of the world-renowned two-wheeler manufacturer based in Pontedera.

It is located in the artfully renovated former ‘Attrezzeria’ (tool shed), one of oldest structures in the factory.

The permanent exhibition is divided into three collections dedicated to the Vespa, Piaggio and Gilera.

The aim of the Alabaster Ecomuseum is to exhibit more than just a simple collection of objects. Instead it displays an entire territory, its history and its chief economic resource. This museum is an exhibition of time and space, a museum of time because of its focus on well-defined historical sectors, while following an extensive period spanning right to the present day; a museum of space because the ecomuseum formula is correlated to the particular geomorphological and environmental features of the district.

The Museum of the Pieve, or small church, of Bientina has been open since 1993 and houses one of the most beautiful collections of religious accessories in noble metal dating back to between the 16th and 18th centuries inclusive.

The display consists of more than 120 objects, including candlesticks, chalices, monstrances, reliquaries, vases and lamps produced by the most renowned silversmiths of the Lucchese, Pisan, Florentine, Neapolitan and French schools.

The rooms of Palazzo Pretorio are home to the Russian Icon Museum, which was founded when a collection was donated by Francesco Bigazzi, a journalist originally from Peccioli and the long time correspondent from Poland and Moscow.

The first section of the museum is devoted to the earliest icons which represent the numerous and various schools of Russian iconography, from the schools of Moscow to those of Kiev or Kazan. It then passes to the more recent icons, such as those of the Bigazzi Collection, merging ancient spirituality with modern mentality.

La Domus Mazziniana, istituita nel 1952, raccoglie l'eredità spirituale e materiale della casa dei Nathan-Rosselli, dove Mazzini fu ospitato fino alla sua morte.

L’edificio fu distrutto nel bombardamento del 31 agosto 1943 e ricostruito nel dopoguerra.

Vi hanno sede il Centro Studi Mazziniani, con un’importante biblioteca sulla storia del Risorgimento, e il museo, che conserva cimeli, medaglie, bandiere, scritti autografi, libri, documenti ed oggetti personali appartenuti a Mazzini.

The centre is housed in the Villa Comunale Baciocchi. The research methods used, the zones explored and the geological features of the Valdera are illustrated by means of explanatory panels that offer a split view of the presences in the zone through Prehistory and during the Etruscan, Roman and Medieval eras.