Located in the medieval monastery of the same name near the river Arno, the National Museum of San Matteo boasts a rich series of works by leading Pisan and Tuscan masters of the 12^th-17^th centuries and a flourishing collection of archaeological and ceramic artifacts. The quantity and value of the exhibits make the San Matteo one of the most important European museums in the field of medieval art.

12^th- and 13^th-century painting is represented by the Croci dipinte (painted crosses), all derived from Pisa’s oldest churches, with works by Berlinghiero Berlinghieri, Giunta Pisano and the Master of San Martino.

The 14^th- and 15^th-century painting section features works by Francesco di Traino, Lippo Menni, Buonamico Buffalmacco, Spinello Aretino, Taddeo di Bartolo and other great painters of the period. Further 15^th-century exhibits include works by Masaccio, Gentile da Fabriano, Beato Angelico, Benozzo Gozzoli and Domenico Ghirlandaio, glazed earthenware from the Della Robbia workshop and the renowned bust-relic of Saint Luxorius, by Donatello.